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James W Hodge Selected Research

Docetaxel (Taxotere)

8/2023Exploiting docetaxel-induced tumor cell necrosis with tumor targeted delivery of IL-12.
1/2021Differential combination immunotherapy requirements for inflamed (warm) tumors versus T cell excluded (cool) tumors: engage, expand, enable, and evolve.
8/2013Chemotherapy-induced immunogenic modulation of tumor cells enhances killing by cytotoxic T lymphocytes and is distinct from immunogenic cell death.
6/2008Combination of docetaxel and recombinant vaccine enhances T-cell responses and antitumor activity: effects of docetaxel on immune enhancement.

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James W Hodge Research Topics

Disease

121Neoplasms (Cancer)
12/2024 - 01/2002
24Carcinoma (Carcinomatosis)
12/2022 - 06/2004
17Prostatic Neoplasms (Prostate Cancer)
11/2018 - 05/2005
16Vaccinia
09/2015 - 01/2002
11Fowlpox
05/2014 - 10/2002
10Neoplasm Metastasis (Metastasis)
10/2017 - 03/2007
7Chordoma
01/2024 - 05/2016
7Breast Neoplasms (Breast Cancer)
01/2021 - 11/2014
4Disease Progression
12/2024 - 01/2007
4Colorectal Neoplasms (Colorectal Cancer)
01/2022 - 09/2002
4Squamous Cell Carcinoma of Head and Neck
01/2020 - 03/2006
4Mouth Neoplasms (Oral Cancer)
01/2020 - 01/2016
4Head and Neck Neoplasms (Head and Neck Cancer)
01/2020 - 04/2017
2Necrosis
08/2023 - 01/2013
2Triple Negative Breast Neoplasms
01/2021 - 04/2016
2Hematologic Neoplasms (Hematological Malignancy)
07/2020 - 08/2008
2Ovarian Neoplasms (Ovarian Cancer)
01/2020 - 01/2003
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
11/2018 - 02/2012
2Lung Neoplasms (Lung Cancer)
08/2014 - 06/2008
1Sinonasal undifferentiated carcinoma
04/2024

Drug/Important Bio-Agent (IBA)

56VaccinesIBA
12/2022 - 01/2002
50AntigensIBA
11/2022 - 01/2002
23Cancer VaccinesIBA
05/2021 - 09/2002
16Carcinoembryonic AntigenIBA
01/2022 - 09/2002
16Neoplasm Antigens (Tumor Antigens)IBA
01/2022 - 10/2004
10Interleukin-15 (Interleukin 15)IBA
04/2024 - 03/2007
10Monoclonal AntibodiesIBA
01/2020 - 06/2005
9Immune Checkpoint InhibitorsIBA
12/2024 - 06/2013
8Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
05/2016 - 10/2002
7avelumabIBA
01/2020 - 06/2016
7Proteins (Proteins, Gene)FDA Link
10/2017 - 01/2006
6Immunoglobulin G (IgG)IBA
11/2018 - 06/2016
6AutoantigensIBA
01/2006 - 01/2002
5Cisplatin (Platino)FDA LinkGeneric
12/2022 - 03/2006
5Cetuximab (Erbitux)FDA Link
12/2021 - 12/2016
5LigandsIBA
12/2021 - 06/2013
5Granzymes (Granzyme)IBA
01/2020 - 02/2012
5PerforinIBA
01/2017 - 09/2002
5Brachyury protein (Brachyury)IBA
12/2016 - 10/2013
4Docetaxel (Taxotere)FDA Link
08/2023 - 06/2008
4T-Cell Antigen Receptors (T-Cell Receptor)IBA
12/2022 - 03/2010
4Chimeric Antigen ReceptorsIBA
12/2021 - 01/2020
4ALT-803IBA
01/2021 - 01/2020
4CytokinesIBA
01/2020 - 07/2009
4PlatinumIBA
01/2020 - 09/2011
4Death Domain ReceptorsIBA
01/2020 - 06/2004
4CalreticulinIBA
12/2016 - 01/2014
4Interleukin-2 (IL2)IBA
12/2016 - 05/2003
4enzalutamideIBA
04/2016 - 11/2013
4PROSTVACIBA
10/2015 - 07/2009
4B7 AntigensIBA
09/2015 - 10/2002
4Prostate-Specific Antigen (Semenogelase)IBA
02/2014 - 05/2005
4CD58 Antigens (LFA-3)IBA
05/2008 - 10/2002
3Interferon-gamma (Interferon, gamma)IBA
04/2024 - 09/2002
3AntibodiesIBA
12/2021 - 12/2016
3RNA (Ribonucleic Acid)IBA
01/2021 - 01/2021
3Histone Deacetylase InhibitorsIBA
01/2020 - 02/2016
3entinostat (MS 275)IBA
01/2020 - 02/2016
3InterleukinsIBA
04/2018 - 03/2007
3EpitopesIBA
01/2017 - 09/2002
3Transcription Factors (Transcription Factor)IBA
06/2016 - 10/2013
3AndrogensIBA
04/2016 - 10/2014
3Sunitinib (Sutent)FDA Link
01/2015 - 04/2012
3Synthetic Vaccines (Recombinant Vaccines)IBA
11/2014 - 12/2007
3Hormones (Hormone)IBA
10/2014 - 01/2007
3Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
03/2007 - 05/2003
2B7-H1 AntigenIBA
12/2021 - 01/2021
2ErbB Receptors (EGF Receptor)IBA
12/2021 - 01/2018
2EnzymesIBA
01/2021 - 05/2014
2Estrogen ReceptorsIBA
01/2021 - 04/2016
2olaparibIBA
01/2020 - 11/2018
2Histone Deacetylases (Histone Deacetylase)IBA
01/2018 - 02/2016
2VorinostatFDA Link
01/2018 - 02/2016
2Twist-Related Protein 1IBA
10/2017 - 09/2015
2Protons (Proton)IBA
12/2016 - 05/2016
2RadiopharmaceuticalsIBA
12/2016 - 07/2008
2Mucin-1 (CA 15-3 Antigen)IBA
05/2016 - 07/2008
2abirateroneIBA
04/2016 - 10/2014
2Androgen Receptors (Androgen Receptor)IBA
04/2016 - 10/2014
2Androgen Receptor AntagonistsIBA
09/2015 - 11/2013
2cabozantinibIBA
01/2015 - 11/2014
2Tyrosine Kinase InhibitorsIBA
01/2015 - 11/2014
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2015 - 11/2014
2Sorafenib (BAY 43-9006)FDA Link
01/2015 - 11/2014
2Adenosine Triphosphate (ATP)IBA
01/2014 - 08/2013
2HMGB1 Protein (HMG1)IBA
01/2014 - 08/2013
2Vinorelbine (Navelbine)FDA LinkGeneric
02/2012 - 09/2011
2Fas Ligand Protein (Fas Ligand)IBA
08/2008 - 06/2004
2Therapeutic UsesIBA
06/2006 - 03/2005
2Peptides (Polypeptides)IBA
01/2006 - 09/2002
1micaIBA
01/2024
1Interleukin-12 (IL 12)IBA
08/2023
1Adenosine (Adenocard)FDA LinkGeneric
05/2023

Therapy/Procedure

58Therapeutics
12/2024 - 01/2003
56Immunotherapy
04/2024 - 06/2003
17Drug Therapy (Chemotherapy)
08/2023 - 01/2006
17Radiotherapy
11/2022 - 06/2003
5Castration
12/2016 - 07/2009
4Aftercare (After-Treatment)
04/2024 - 01/2012
2Immunomodulation
08/2014 - 08/2014